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In endosomes, Fe 3+ is reduced to Fe 2+ , which is then released from the endosomes into the cytoplasm, while the excess iron is retained in ferritin

Compared to the wild-type, ETTzf / homozygous fish exhibited no differences in morphology, behavior or tissue histology, where EGT content was 1000 times less and 8-oxoguanine indicative of oxidative damage was 3.8 times higher [65]