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p-JNK induces the opening of the mitochondrial permeability transition (MPT) pore, increasing the mitochondrial permeability and the pore transition ( Nuclear factor erythroid 2-related factor 2 (Nrf2) is a transcription factor encoded by the NFE2L2 gene that NAPQI can indirectly activate

[Abstract]2019 May 31;132(11):jcs224071

Blockade of NMDA receptors and apoptotic neurodegeneration in the developing brain

Further studies are now required to elucidate which combinations of energy substrates and AMP precursors will be best to facilitate rapid restoration of ATP in astrocytes