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doi: 10.1038/ng.764 61 FrankeAMcGovernDPBarrettJCWangKRadford-SmithGLAhmadTet al

3 Components of oxidative stress and their contributions to IBD pathogenesis 3.1 ROS in IBD pathogenesis The superoxide anion (O2), which is produced when molecular oxygen gains one electron, is the most prevalent free radical in human tissues (101)