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Further, pathway-based functional prediction from the Kyoto Encyclopaedia of Genes and Genomes (KEGG) database revealed that steroid biosynthesis, sphingolipid metabolism and tryptophan metabolism were varied between the pre-dose faecal samples in the above-mentioned groups of mice

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an antibody that specifically binds to an EphA2 polypeptide comprises a VH CDR2 having the amino acid sequence of SEQ ID NOS.: 6, 16, 26, 36, 46, 56, or 66, and a VH CDR3 having the amino acid sequence of SEQ ID NOS.: 7, 17, 27, 37, 47, 57, or 67