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However, an exaggerated inflammatory response can lead to tissue damage and impaired healing

The reaction proceeds in two steps, which occur at distinct active sites: one located at the N-terminal and the other at the C-terminal region of the enzyme

However, it can lead to side effects, including immune cell death, bone marrow impairment, liver and kidney damage, cachexia (severe weight loss and muscle wasting), and secondary tumorigenesis

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