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doi: 10.3389/fnmol.2023.1113081 Received 01 December 2022 Accepted 06 March 2023 Published 23 March 2023 Volume 16 - 2023 Edited by Sara Anna Bonini, University of Brescia, Italy Reviewed by Franca Codazzi, San Raffaele Hospital (IRCCS), Italy

Ferroptosis, a recently identified ferroptosis-dependent pathological process characterized by peroxidation and the inactivation of GSH and GPX4, has been shown to be induced by the CCH-mediated inactivation of System Xc-associated transporter proteins ( Our metabolomic analysis showed that, when compared to 2VO group expression, most of the DEMs in RY-A were enriched in fatty acid biosynthesis (ko00061), biosynthesis of unsaturated fatty acids (ko01040), ferroptosis (ko04216), and glutathione metabolism (ko00480)

The sleep change is often described as returning to a quality of rest they had in their late 20s: falling asleep faster, fewer nighttime awakenings, and waking up feeling more genuinely rested rather than just having logged enough hours

Upon exposure to a 660 nm laser (0.1 W/cm 2 for 5 min), the DCFH fluorescence intensity in the HMO + laser group was markedly higher compared to the group without laser irradiation