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Nevertheless, genetic variation only explains a minor part of interindividual variability, suggesting regulation by nuclear receptors, PAPS-cofactor availability and inhibition by various drugs and environmental compounds could be major determinants of variability in SULT activity 15

Recent studies have also evaluated the clinical utility of DNA methylation hotspots as prognostic biomarkers for BLCA

The graphical representation in Figure 2 illustrates the plasma concentration profiles of Treatment A and Treatment B over different time intervals