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Gl EM, Sherman AD (1978) Synthesis and metabolism of L-kynurenine in rat brain

These are the mechanisms most often cited for its cosmetic use

NF-B is also a key factor in regulating NADPH oxidase expression and it is possible that there is a positive feedback loop in which NF-B activation by oxidative stress leads to further radical production via NADPH oxidase (Nikolova et al., 2005