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42 Taken together, these milestones highlight the intricate interplay between microbial communities and tumors, advancing development in the field of cancer microbiology

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Glioma A previous analysis based on The Cancer Genome Atlas (TCGA) RNA sequencing data suggested lower expression of ACSL1 influences metabolic reprogramming and contributes to the better survival of patients with isocitrate dehydrogenase 1 (IDH1) mutant glioma (Zhou et al., 2019)

We scored individuals across all cohorts as outliers for a given organ age gap using a two standard deviation cutoff and clustered individuals into extreme aging types (e-ageotypes) (Fig