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Multiple lines of evidence support a role for reactive nitrogen species (RNS) in degeneration of this pathway, specifically nitric oxide (NO)

If this happens in one pregnancy, there is a slightly greater risk that it could happen in any further pregnancies

Human Uterine Leiomyomata Express Higher Levels of Peroxisome Proliferator-Activated Receptor Gamma, Retinoid X Receptor Alpha, and All-Trans Retinoic Acid Than Myometrium

5.2 Clinical studies 5.2.1 Neurodegenerative diseases Preliminary clinical studies suggest that IF may regulate cognitive function through various metabolic pathways, including ketone body synthesis and degradation, butyrate metabolism, pyruvate metabolism, and glycolysis and gluconeogenesis pathways (156)