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However, while early-phase trials reported favorable findings, later studies yielded mixed results, with some phase II trials failing to show significant improvement in negative symptoms (Umbricht et al

(PubMed) Begin MJ, Ste-Marie LG, Coupal L, Ethier J, Rakel A

Notably, when compared to other white blood cells such as macrophages and lymphocytes, neutrophils exhibit the highest rate of glutamine consumption [143,144,145]