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In recent years, IDH inhibitors targeting IDH mutants, including ivosidenib and enasidenib (Table 1), have been approved by the Food and Drug Administration to be used in patients with IDH1 or IDH2 mutant recurrent or refractory AML, respectively (Kim, 2017

(2) somatostatin, which inhibits release and shapes the trough between pulses

Kiros TG, Levast B, Auray G, Strom S, van Kessel J, Gerdts V

Mitochondrial isolation To obtain the mitochondrial fraction, cell pellets were frozen at 80 C and homogenized (1012 strokes) in a glass-Teflon PotterElvehjem homogenizer in buffer A (83 mM sucrose and 10 mM MOPS