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"Vitamin B12 deficiency and use of proton pump inhibitors: a systematic review and meta-analysis"

They found 2812 genes and 149 miRNAs (human and EBV) to be differentially expressed in NP460, HK1, C666, and X666 with RNASeq and 533 miRNA-mRNA target pairs were inversely regulated in the three NPC cell lines compared to NP460 cells

In this model, HEPs decreased the production of reactive oxygen species from 80% to 58% in a dose-dependent manner, and increased the efficacy of free radical scavenging