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317 Neurodegenerative disorders and protein homeostasis Neurodegenerative disorders (NDDs) are characterized by a progressive loss of neuronal structure and function, leading to cognitive, motor, and behavioral impairments

Recent research has revealed that the relationship between the TME and tumor metabolic reprogramming is not one of simple causality but rather forms a dynamic, bidirectional, and self-reinforcing vicious cycle [12, 13]

Tirzepatide engages an additional GIP-receptor pathway and often breaks plateaus where semaglutide alone has slowed

According to the authors, the peptide was administered intranasally and showed an excellent safety profile with no side effects, but the investigators did not report data on its nootropic effects [51]