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R.HennigM

This specific bond is important because it makes the molecule more stable and resistant to being broken down by certain enzymes in the body

Baseline reductions in structural connectivity also predict progression to poor cognitive outcomes at 3-year follow-up 141 and in PD patients with MCI they predict progression to dementia within 5 years 144 , with interhemispheric frontal and parietal connections being most implicated in cognitive impairment 141,144,145