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Cerebral Metabolism Studies The regional cerebral metabolic rates for glucose (rCMRglc) were measured using the quantitative autoradiographic [ 14 C]2-deoxy-D-glucose technique in groups of five to seven male, Fischer-344, conscious rats at 30 min after IV administration of saline or ALCAR 250750 mg/kg and at 20 min after IV saline or KET 20 mg/kg (Ori et al., 2002

"Mitochondrial decay in the aging rat heart: evidence for improvement by dietary supplementation with acetyl-L-carnitine and/or lipoic acid." Annals of the New York Academy of Sciences

Specifically, SRC-1 promotes energy expenditure, SRC-2 supports energy storage and mitochondrial function, while SRC-3 regulates energy substrate utilization and affects muscle endurance [56, 57]