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As a scavenger of toxic free radicals, GSNO is 100-fold more potent in neutralizing ROS than GSH and is further metabolized by an evolutionary conserved enzyme S-nitrosoglutathione reductase (GSNOR) at the expense of NADH to generate GSSG and ammonia (Figure 3)

This immunosuppression may be associated with increased susceptibility to viral, protozoal, and fungal infections

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Shmerling, MD, Senior Faculty Editor, Harvard Health Publishing Data on life expectancy in the United States (U.S.) has been collected since 1900 and, with rare exceptions, has consistently increased