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Because the A1 and A2 subtypes of the adenosine receptor, which are involved in glucose absorption in skeletal muscles, are antagonistic to one another, acute caffeine treatment reduces insulin resistance and glucose tolerance

Ipamorelin# Ipamorelin (Aib-His-D-2-Nal-D-Phe-Lys-NH2) is a pentapeptide that also acts through GHS-R1a but with a binding profile that produces clean, selective GH release

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