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Therefore, reactive astrocytes may not only produce fewer antioxidant molecules in the HD brain, but they might also release more pro-oxidant factors (Ben Haim et al., Furthermore, mHTT has been shown to reduce astrocytic release of BDNF (Wang et al., 2012

Dysregulation of the Hippo signaling pathway, particularly through the inactivation of LATS1/2, results in the activation of YAP

Xu L, Li W, Chen S, Zhong G, Liu H, Xiu L, Yu X, Chen F, Li N, Lv Y (2020) Effects of a combination of Japanese raisin tree seed and flower of lobed kudzuvine against acute alcohol-induced liver injury in mice