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MAZ51 is a potent inhibitor of VEGFR3 kinase activity, which only weakly affects the related receptor tyrosine kinase VEGFR2 62,63

doi: 10.1128/spectrum.01147-21 155 YachidaSMizutaniSShiromaHShibaSNakajimaTSakamotoTet al

In contrast, GLUT1 labelling is significantly reduced in astrocytes in the optic nerve in early disease in the DBA/2J, while GLUT3 labelling in axons remained unchanged (83)