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Description

The potential for receptor desensitization over extended periods is a theoretical concern with any agent that continuously stimulates a receptor

Supplementary information Supplementary Tables 1 and 2 Source data Unprocessed western blots Source Data Fig

Ras: rat sarcoma

To establish a direct association between HMGA1 and HK2 transcription, we introduced mutations into the HMGA1 binding sites within the HK2 promoter and subsequently conducted a luciferase reporter assay to evaluate HMGA1s specific binding capability to the HK2 promoter