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Cell Res (2013) 23:898914

In RIN-m5F cells, UA increases the mRNA expression of inflammatory mediators, including chemokine (C-X-C motif) ligand 1 (CXCL-1 or KC), monocyte chemoattractant protein-1 (MCP-1), and interleukin-6 (IL-6) [30]

UK guidelines, primarily from NICE Clinical Knowledge Summary and the British National Formulary (BNF), provide evidence-based recommendations for treatment