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Reciprocally, it is the binding of tetramers to form the enzyme filament that restricts the flexibility of lids and to adopt a conformation that closes over the substrate sites for enzymatic activity

Card9-dependent IL-1 regulates IL-22 production from group 3 innate lymphoid cells and promotes colitis-associated cancer

201 , e00367-19 (2019)

[DOI] [PubMed] [Google Scholar] 113.Murakami T., Miyakoshi M., Araho D., Mizutani K., Kambara T., Ikeda T., Chou W.H., Inukai M., Takenaka A., Igarashi K