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We further employed 6 SNPs detected from Anstee et al., GWAS data for the sensitivity analysis and observed that liability to NAFLD also had positive association with vitamin B12 concentrations (Beta, 0.04

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When this enzyme shuts down, the methylation cycle stalls, leading to a vicious cycle where the body cannot produce the very antioxidants (like glutathione, which relies on downstream methylation pathways) needed to clear the viral-induced oxidative stress

National Health and Nutrition Examination Survey data found that the normal serum MMA range for the 2.5th to 97.5th percentile of people 70 years, who were considered to be vitamin B12-replete and with normal kidney function, was 84 to 317 nmol/l (Mineva, 2019)