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When NAD+ levels are adequate, SIRT1 activity increases, promoting DNA repair, reducing inflammation, and enhancing stress resistance

Preclinical safety data from 11-day and 28-day murine studies show no hepatotoxicity, nephrotoxicity, or hematological abnormalities at doses up to 100mg/kg daily

Its incredibly rewarding to see it now progressing through multi-center FDA trials and gaining peer-reviewed clinical validation

Separately, GHK-Cu has been found to stimulate fibroblast proliferation while upregulating genes for collagen, elastin, dermatan sulfate, chondroitin sulfate, and decorin key structural components of the skin's extracellular matrix and to modulate matrix metalloproteinases (MMPs) and their inhibitors, which supports balanced remodeling rather than excessive breakdown or fibrosis