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Description

First, recent studies have shown that ASIC1a inhibition by the non-specific ASIC antagonist amiloride is protective in a rat model of epileptic seizures (Liang et al., 2015)

Cell Rep (2017) 20(7):1692704

We compared human aortic smooth muscle cells (HASMCs) with and without CRISPR-Cas9 editing of the Loxl2 gene (HASMC T1) to test whether LOXL2 depletion correlates with loss of BHZ incorporation signal and to determine the specificity of the assay