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Animal blank sera were prepared from 20 individual Sprague Dawley rats and 20 individual Cynomolgus monkeys

The antioxidant transcriptome is particularly relevant given the high oxidative burden in aged neural tissue

Decreased HHIP expression relieves inhibition of PKM2, accelerating glycolysis and lactate production to promote cell proliferation ( 4.3.2 Key cytokines and signaling pathways IL-4 and IL-13 are secreted by Th2 cells and mast cells, activating the STAT6 pathway to promote ASMC proliferation and goblet cell mucus secretion, while upregulating PTGES expression to initiate the PTGES-AKT-HIF-1 pathway

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