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The detection limit for ALP is lower than 0.3 M in 4 min

M., Ari, C., Seyfried, T

MDR1 which is highly expressed at the BBB endothelium encodes for ABCB1 (P-glycoprotein) which shows decreased expression in the case of PD patients and leads to progression of PD [117]

Recent evidence indicates that iron dyshomeostasis and ferroptotic processes directly compromise BBB integrity, thereby facilitating the influx of pathological factors and promoting neuroinflammatory propagation, which accelerates the progression of Alzheimers disease (AD) (Xu et al., 2024