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83 Additionally, GTP cyclohydrolase 1 prevents ferroptosis through its metabolites dihydrobiopterin and tetrahydrobiopterin (BH4)

Briefly, the cells were incubated for 24 h with NiCl 2 in the concentration range of 0.510 mM

[DOI] [PMC free article] [PubMed] [Google Scholar] 136.Farokhnia M., Azarkolah A., Adinehfar F., Khodaie-Ardakani M.R., Hosseini S.M.R., Yekehtaz H., Tabrizi M., Rezaei F., Salehi B., Sadeghi S.M.R., et al

Under the action of acidic lysosomal enzymes, the wrapped substances are degraded to achieve intracellular environmental homeostasis and organelle renewal