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J Trace Elem Med Biol 41:119128

J Proteome Res 14:15351546 Hammond DE, Mageean CJ, Rusilowicz EV, Wickenden JA, Clague MJ, Prior IA (2015b) Differential reprogramming of isogenic colorectal cancer cells by distinct activating KRAS mutations

They are degradation products of mature collagen fibres in the extracellular matrix, proportional to the activity of osteoclasts, and are released into the bloodstream and excreted in the urine during bone resorption