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Oxidative stress, molecular inflammation and sarcopenia

Y., Tyurin V

HegedsKFehrCJalsovszkyIKristfZRohonczyJVassEet al

The presence of three chiral centers in the saturated side chain, presenting as either R- or S-configuration, leads to eight different stereoisomers, among which only -tocopherol in its RRR conformation is selectively retained and incorporated into lipoproteins, while non--tocopherol congeners are preferentially metabolized and excreted (Podszun and Frank 2021)