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HED = animal dose Km_animal/Km_human

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Delayed vaccine-induced CD8 + T cell expansion by topoisomerase I inhibition mediates enhanced CD70-dependent tumor eradication

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355 SDH plays a crucial role in T-cell metabolic and epigenetic control, with its deficiency inducing proinflammatory gene expression and promoting Th1 and Th17 cell differentiation

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