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DSIP Clinical Evidence Context Human evidence A handful of small placebo-controlled studies in chronic insomniacs from 1981-1987 reported modest improvements in total sleep time, sleep efficiency, and daytime function

Numerous studies have conducted phenotypic, genomic, epigenomic, transcriptomic, and proteomic analyses, utilized disease models to explore potential inhibitors, and evaluated candidate small-molecule drugs in clinical settings (115)

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