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R.MiyataT.KimA.PathakV.et al (2023a)

Optimizing timing helps on both fronts

For neurodegenerative diseases like PD, RVG29-linked PLGA NPs were developed to deliver miR-124, downregulating the MEKK3/NF-B pathway and reducing pro-inflammatory cytokines like tumor necrosis factor- (TNF-), IL-6, and iNOS, enhancing neuroprotection in a PD model