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[68] TEMPOL and similar SOD-mimetic nitroxides exhibit a multiplicity of actions in diseases involving oxidative stress

An example is B003-2A, a recently developed IGF-1R anti-idiotypic antibody antagonist, which abrogated the IGF-1R-mediated proliferation of ovarian cancer cells in vivo and in vitro and overcame resistance to cisplatin in ovarian cancer cell lines (64, 74)

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393 Alternate day fasting (ADF) improves cardiovascular marker levels, including reduced fat mass, an improved fat-to-lean ratio, and increased -HB-hydroxybutyrate levels, suggesting its clinical relevance for CVD intervention