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Description

The competition between NAD + salvage and the methylation of NAM suggests that NNMT may reduce the oxidation of fuel and increase the storage of fat by regulating the formation of NAD + (Trammell and Brenner, 2015)

It stimulates lipolysis (breakdown of stored fats) and inhibits lipogenesis (formation of new fat), primarily via activation of -adrenergic and AMP-activated protein kinase (AMPK) pathways