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Owing to their small size, high surface-volume ratio, high stability, and unique physicochemical properties, nano/microcarriers can be utilized to incorporate hydrophilic and hydrophobic drugs as well as other biologics

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After 4 weeks of diet feeding, animals started receiving sodium nitrite injections (25 mg per kg (body weight) intraperitonially) three times a week for the remainder of the study

Strategies targeting KRAS indirectly include 1) inhibiting the nucleotide exchange cycle, 2) disrupting membrane localization and KRAS processing, and 3) inhibiting downstream signaling pathways