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Prolotherapy is particularly effective for: Ligament laxity and instability (knees, ankles, shoulders) Tendinopathies and tendon tears Chronic low back pain from ligament weakness Joint instability Sacroiliac joint dysfunction Conditions that have failed to improve with other conservative treatments PRP (Platelet-Rich Plasma) Therapy PRP therapy uses a concentrated preparation of the patients own blood platelets drawn, processed, and re-injected into the damaged area

Additionally, circulating CD38 + lymphocytes and plasmablasts were found to be elevated in SSc 23

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