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Studies have found that Trx has a differential inhibitory effect on MMP-9, MMP-2, TIMP-1 and TIMP-2, thereby regulating the MMP/TIMP balance

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In addition, some investigators found that USP22 and lncRNA PART1 expression was decreased in a MIR injury model

A systematic review by Palombella demonstrated that, compared to FBS, HPL can enhance the proliferation of adipose stem cells (ASCs) and bone marrow stem cells (BMSCs) by increasing the doubling rate and reducing the doubling time (Palombella et al., 2022)