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Role of multidrug resistance-associated protein 1 in the pathogenesis of allergic airway inflammation

70 The first prospective trial testing the addition of metformin to DOTS, the Metformin for TB/HIV Host-directed Therapy (METHOD) trial, is currently in planning and will evaluate the proportion of smear negative TB patients at month two post-treatment

i) Inducing ferroptosis to reverse targeted therapy resistance

The closest safety dataset is the Increlex (mecasermin) clinical program , which followed 71 pediatric patients with severe primary IGFD on twice-daily SubQ rhIGF-1 for a mean of 3.9 years (some patients up to 11.5 years)