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However, given the pre- and postsynaptic expression of D3 receptors in different limbic structures, these data cannot be conclusive, pointing to the importance to test the effects of pharmacological agents acting on D3R receptors on motivational impairment (Neill et al., 2016

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Correlation studies of haplotype, muscle gene expression and protein characterization, could help understanding the pathophysiological mechanisms of this myopathic presentation of hypothyroidism

Furthermore, most studies show that changes in lifestyle are associated with improvements in cardiovascular disease (CVD) risk variables, including insulin resistance and blood cholesterol levels