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Brain levels of these apoE fragments were present at much higher levels in AD patients than in age- and sex-matched nondemented controls, with an apoE4 gene dose-dependent effect (Harris et al., 2003

Nevertheless, the GSTM1*0/GSTT1*0 genotype has been shown to be a potential genetic risk factor for essential hypertension (40), and it has been reported that genetic loss of the GSTT1 enzyme is an independent and powerful predictor of premature vascular morbidity and death in individuals with type 2 diabetes (41)

64 The diagnostic value of N 6 -methylandenosine (m 6 A)-related lncRNAs has also been demonstrated in prognostic models incorporating m 6 A-LPS, age, and WHO grade, effectively predicting OS in LGG patients

Likewise, MUC1 was more prevalently increased under chronic hypoxia in TNBC cell lines but not in ER + breast cancer cell lines (Fig