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Body composition in DIO mice with/without NNMT inhibition showing reduced WAT mass with preserved lean mass relative to diet-matched controls [1,3,4]

Tibsovo is joined in this indication by a companion diagnostic, Abbott Laboratories RealTime IDH1 Assayalso approved Tuesdaywhich physicians can use to identify patients eligible for Tibsovo treatment

The efficacy of lorcaserin appears similar to that of orlistat (mean difference in weight loss between active and placebo treated groups approximately 3 to 4 kg) and perhaps slightly less than that of phentermine-topiramate