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10.1021/jf100538t 197 Xiao-FangP.KaWingC.JinyuM.BoC.ChiTangH.CliveL.et al (2008)

There is increasing evidence to suggest that the significant disruption of mitochondrial function involving multiple deficiencies in oxidative phosphorylation via the mitochondrial electron transport chain, secondary to inhibition of the TCA cycle [25, 38] culminates in a synergistic impairment of energy metabolism and depletion of cellular energy stores [2, 29]