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For most women, the clinical conversation ends at oral contraceptives for cycle regulation, metformin for insulin resistance, and the diffuse instruction to "lose weight." What it rarely includes is any serious engagement with the signaling dysfunctions that make PCOS resistant to those blunt interventions in the first place

You can browse this work through these animal-model studies on PubMed

This might include a cholecystectomy (removal of the gallbladder) or other surgical interventions

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