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The supernatant was dialyzed against potassium phosphate buffer (3 ml, 100 mm, pH 8.0) containing 0.05 mm PLP, 0.1 mm DTT and 0.1 mm EDTA for 24 h at 4C under dark conditions, which was used for enzyme assays

537 Mitochondria transplantation Mitochondrial transfer between cells is an important way to maintain intercellular homeostasis, which can also help to rescue damaged cells or give them new properties

Conversely, if repeated sets of data obtained for each patient are analyzed independently, it can be concluded that uridine (FRDA1), or the simultaneous presence of uridine and pyruvate (FRDA1 to 4) exerts a statistically confirmed effect for 4 of the 5 patients (Figures 3 and 4)

4.3 Cigarette smoke: the ferroptosis catalyst in COPD CS is the primary driver of COPD, acting as a potent catalyst for ferroptosis via multiple interconnected mechanisms