fsp1 is a glutathione-independent ferroptosis suppressor.

fsp1 is a glutathione-independent ferroptosis suppressor. Regulatory pathways independent of GPX4 causes ferroptosis. FSP1: Upregulation of CoQ shifts ferroptosis

Name: fsp1 is a glutathione-independent ferroptosis suppressor. Regulatory pathways independent of GPX4 causes ferroptosis. FSP1: Upregulation of CoQ shifts ferroptosis
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Upregulation of CoQ shifts ferroptosis dependence from GPX4 to FSP1 in acquired radioresistance ScienceDirect The suppression of FSP1 expression via NRF2 promotes ferroptosis induced by reactive oxygen species in vascular smooth muscle cells ScienceDirect FSP1 is a glutathione independent ferroptosis suppressor ORCA Structure and Function of FSP1 Encyclopedia MDPI

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The wildtype selenium-containing crystal structure is structurally similar to previously reported mutant GPX4 structures as compared in a previous study [50]