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M.ManfronJ.MonteiroL

doi: 10.1210/jc.2018-02496 7 ChenZJZhaoHHeLShiYQinYShiYet al

Abstract The imposition of environmental stresses on plants brings about disturbance in their metabolism thereby negatively affecting their growth and development and leading to reduction in the productivity

The unique Cys-158 residue in ApoE2 disrupts the salt bridge between Arg-158 and Asp-154 and forms a new salt bridge between Arg-150 and Asp-154, leading to reduced affinity for the low-density lipoprotein receptor (LDLR) (Dong et al., 1994)