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However, these alterations to the microbial abundance and composition at the phylum, family and genus levels may not sufficient to adequately clarify the changes to the gut microbiota in DN patients, further investigations at the levels of species or strains are necessary in the future

A prominent example is their inhibition of the PI3K/Akt pathwayGA treatment in lung cancer cells led to downregulation of PI3K/Akt alongside increased p53 levels, which in turn activated downstream executioner caspases and cell cycle inhibitors (p21Cip1/p27Kip1), culminating in apoptosis and growth arrest (151)