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Unveiling the nongenomic actions of thyroid hormones in adult mammalian brain: the legacy of Mary B

This represents a paradigm shift in non-surgical obesity treatment

Replacement of Tyr110 in recombinant Y110A decreased both k cat app and 1/ values for the disulfide substrate and GSH in the GSSCys and HEDS assay (Supplementary Figs 18 and 19)